Promising Approaches to Optimize the Biological Properties of the Antimicrobial Peptide Esculentin-1a(1–21)NH2: Amino Acids Substitution and Conjugation to Nanoparticles

Antimicrobial peptides (AMPs) represent an interesting class of molecules with expanding biological properties which make them a viable alternative for the development of future antibiotic drugs. However, for this purpose, some limitations must be overcome: (i) the poor biostability due to enzymatic...

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Bibliographic Details
Main Authors: Bruno Casciaro, Floriana Cappiello, Mauro Cacciafesta, Maria Luisa Mangoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2017-04-01
Series:Frontiers in Chemistry
Subjects:
Online Access:http://journal.frontiersin.org/article/10.3389/fchem.2017.00026/full