Molecular and Cellular Mechanisms that Induce Arterial Calcification by Indoxyl Sulfate and P-Cresyl Sulfate

Molecular and Cellular Mechanisms that Induce Arterial Calcification by Indoxyl Sulfate and P-Cresyl Sulfate

The protein-bound uremic toxins, indoxyl sulfate (IS) and p-cresyl sulfate (PCS), are considered to be harmful vascular toxins. Arterial media calcification, or the deposition of calcium phosphate crystals in the arteries, contributes significantly to cardiovascular complications, including left ven...

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Bibliographic Details
Main Authors: Britt Opdebeeck, Patrick C. D’Haese, Anja Verhulst
Format: Article
Language:English
Published: MDPI AG 2020-01-01
Series:Toxins
Subjects:
uremic toxins
arterial calcification
lipid metabolism
inflammation
coagulation
endothelial dysfunction
epigenetics
Online Access:https://www.mdpi.com/2072-6651/12/1/58

Internet

https://www.mdpi.com/2072-6651/12/1/58

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