Immunostimulatory Endogenous Nucleic Acids Perpetuate Interface Dermatitis—Translation of Pathogenic Fundamentals Into an In Vitro Model

Immunostimulatory Endogenous Nucleic Acids Perpetuate Interface Dermatitis—Translation of Pathogenic Fundamentals Into an In Vitro Model

Interface dermatitis is a histopathological pattern mirroring a distinct cytotoxic immune response shared by a number of clinically diverse inflammatory skin diseases amongst which lichen planus and cutaneous lupus erythematosus are considered prototypic. Interface dermatitis is characterized by pro...

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Bibliographic Details
Main Authors: Christine Braegelmann, Tanja Fetter, Dennis Niebel, Lara Dietz, Thomas Bieber, Joerg Wenzel
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-01-01
Series:Frontiers in Immunology
Subjects:
interface dermatitis/lichenoid tissue reaction
nucleic acid sensing
damage associated molecular patterns (DAMPs)
type I immunity
lupus erythematosus
lichen planus
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2020.622511/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2020.622511/full

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