Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo.

Influence of nanoparticle-mediated transfection on proliferation of primary immune cells in vitro and in vivo.

INTRODUCTION:One of the main obstacles in the widespread application of gene therapeutic approaches is the necessity for efficient and safe transfection methods. For the introduction of small oligonucleotide gene therapeutics into a target cell, nanoparticle-based methods have been shown to be highl...

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Main Authors: Susanne Przybylski, Michaela Gasch, Anne Marschner, Marcus Ebert, Alexander Ewe, Gisa Helmig, Nadja Hilger, Stephan Fricke, Susanne Rudzok, Achim Aigner, Jana Burkhardt
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5412997?pdf=render

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http://europepmc.org/articles/PMC5412997?pdf=render

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