Delivery Systems for the Direct Application of siRNAs to Induce RNA Interference (RNAi) In Vivo

by Achim Aigner
Published 2006-01-01

Drug Delivery by Ultrasound-Responsive Nanocarriers for Cancer Treatment

by Kristin Entzian, Achim Aigner
Published 2021-07-01

Inhibition of HER Receptors Reveals Distinct Mechanisms of Compensatory Upregulation of Other HER Family Members: Basis for Acquired Resistance and for Combination Therapy

by Daniela Gutsch, Robert Jenke, Thomas Büch, Achim Aigner
Published 2021-01-01

Tyrosine-Modification of Polypropylenimine (PPI) and Polyethylenimine (PEI) Strongly Improves Efficacy of siRNA-Mediated Gene Knockdown

by Sandra Noske, Michael Karimov, Achim Aigner, Alexander Ewe
Published 2020-09-01

Anticancer Therapy with HDAC Inhibitors: Mechanism-Based Combination Strategies and Future Perspectives

by Robert Jenke, Nina Reßing, Finn K. Hansen, Achim Aigner, Thomas Büch
Published 2021-02-01

Targeted CRM197-PEG-PEI/siRNA Complexes for Therapeutic RNAi in Glioblastoma

by Achim Aigner, Chantal C.M. Appeldoorn, Sabrina Höbel, Pieter J. Gaillard
Published 2011-12-01

Enhanced Antitumorigenic Effects in Glioblastoma on Double Targeting of Pleiotrophin and Its Receptor ALK

by Marius Grzelinski, Florian Steinberg, Tobias Martens, Frank Czubayko, Katrin Lamszus, Achim Aigner
Published 2009-02-01

Biokinetic datasets of PEI F25-LMW complexed and non-complexed 32P-siRNA within different lung compartments

by Jens Lipka, Manuela Semmler-Behnke, Alexander Wenk, Jana Burkhardt, Achim Aigner, Wolfgang Kreyling
Published 2016-06-01

Role of Chemosensory TRP Channels in Lung Cancer

by Thomas R. H. Büch, Eva A. M. Büch, Ingrid Boekhoff, Dirk Steinritz, Achim Aigner
Published 2018-09-01

SATB1-Mediated Upregulation of the Oncogenic Receptor Tyrosine Kinase HER3 Antagonizes MET Inhibition in Gastric Cancer Cells

by Robert Jenke, Miriam Holzhäuser-Rein, Stefanie Mueller-Wilke, Florian Lordick, Achim Aigner, Thomas Büch
Published 2021-12-01

Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner

by Irina Kiprianova, Janina Remy, Nelli Milosch, Isabelle V. Mohrenz, Volker Seifert, Achim Aigner, Donat Kögel
Published 2015-07-01

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

by Ulrike Weirauch, Nadine Beckmann, Maren Thomas, Arnold Grünweller, Kilian Huber, Franz Bracher, Roland K. Hartmann, Achim Aigner
Published 2013-07-01

Functional Role and Therapeutic Potential of the Pim-1 Kinase in Colon Carcinoma

by Ulrike Weirauch, Nadine Beckmann, Maren Thomas, Arnold Grünweller, Kilian Huber, Franz Bracher, Roland K. Hartmann, Achim Aigner
Published 2013-07-01

Evaluation of Colon-Specific Plasma Nanovesicles as New Markers of Colorectal Cancer

by Inga Nazarova, Maria Slyusarenko, Elena Sidina, Nadezhda Nikiforova, Vladislav Semiglazov, Tatiana Semiglazova, Achim Aigner, Evgeny Rybakov, Anastasia Malek
Published 2021-08-01

Glioblastoma Tissue Slice Tandem-Cultures for Quantitative Evaluation of Inhibitory Effects on Invasion and Growth

by Vasile Sidorcenco, Luisa Krahnen, Marion Schulz, Janina Remy, Donat Kögel, Achim Temme, Ute Krügel, Heike Franke, Achim Aigner
Published 2020-09-01

Targeted RNAi of BIRC5/Survivin Using Antibody-Conjugated Poly(Propylene Imine)-Based Polyplexes Inhibits Growth of PSCA-Positive Tumors

by Willi Jugel, Achim Aigner, Susanne Michen, Alexander Hagstotz, Alexander Ewe, Dietmar Appelhans, Gabriele Schackert, Achim Temme, Stefanie Tietze
Published 2021-05-01

Therapeutic Targeting of Stat3 Using Lipopolyplex Nanoparticle-Formulated siRNA in a Syngeneic Orthotopic Mouse Glioma Model

by Benedikt Linder, Ulrike Weirauch, Alexander Ewe, Anja Uhmann, Volker Seifert, Michel Mittelbronn, Patrick N. Harter, Achim Aigner, Donat Kögel
Published 2019-03-01

Analysis of Transcriptional Regulation of the Human miR-17-92 Cluster; Evidence for Involvement of Pim-1

by Roland K. Hartmann, Achim Aigner, Arnold Grünweller, Dennis Streng, Julia Schlereth, Lara Golde, Kerstin Lange-Grünweller, Dorothee Hartmann, Maren Thomas
Published 2013-06-01

Differential Regulation of a Fibroblast Growth Factor-Binding Protein during Skin Carcinogenesis and Wound Healing

by Andreas Kurtz, Achim Aigner, Rafael H. Cabal-Manzano, Robert E. Butler, Dozier R. Hood, Roy B. Sessions, Frank Czubayko, Anton Wellstein
Published 2004-09-01

Polyethylenimine Nanoparticle-Mediated siRNA Delivery to Reduce α-Synuclein Expression in a Model of Parkinson’s Disease

by Christin Helmschrodt, Sabrina Höbel, Sandra Schöniger, Anne Bauer, Jana Bonicelli, Marieke Gringmuth, Simone A. Fietz, Achim Aigner, Angelika Richter, Franziska Richter
Published 2017-12-01