Structural Determinants of Substrate Specificity of SplF Protease from <i>Staphylococcus aureus</i>

Structural Determinants of Substrate Specificity of SplF Protease from <i>Staphylococcus aureus</i>

Accumulating evidence suggests that six proteases encoded in the <i>spl</i> operon of a dangerous human pathogen, <i>Staphylococcus aureus</i>, may play a role in virulence. Interestingly, SplA, B, D, and E have complementary substrate specificities while SplF remains to be c...

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Bibliographic Details
Main Authors: Natalia Stach, Abdulkarim Karim, Przemyslaw Golik, Radoslaw Kitel, Katarzyna Pustelny, Natalia Gruba, Katarzyna Groborz, Urszula Jankowska, Sylwia Kedracka-Krok, Benedykt Wladyka, Marcin Drag, Adam Lesner, Grzegorz Dubin
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
serine protease, substrate specificity, crystal structure, virulence factor, <i>Staphylococcus</i> <i>aureus</i>
Online Access:https://www.mdpi.com/1422-0067/22/4/2220

Internet

https://www.mdpi.com/1422-0067/22/4/2220

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