Hyaluronan Degradation by Cemip Regulates Host Defense against Staphylococcus aureus Skin Infection

Summary: Staphylococcus aureus is a major human bacterial pathogen responsible for deep tissue skin infections. Recent observations have suggested that rapid, localized digestion of hyaluronic acid in the extracellular matrix (ECM) of the dermis may influence bacterial invasion and tissue inflammati...

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Bibliographic Details
Main Authors: Tatsuya Dokoshi, Ling-juan Zhang, Fengwu Li, Teruaki Nakatsuji, Anna Butcher, Hiroyuki Yoshida, Masayuki Shimoda, Yasunori Okada, Richard L. Gallo
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719316407