Cationic Polyamidoamine Dendrimers as Modulators of EGFR Signaling In Vitro and In Vivo.

Cationic polyamidoamine (PAMAM) dendrimers are branch-like spherical polymers being investigated for a variety of applications in nanomedicine including nucleic acid drug delivery. Emerging evidence suggests they exhibit intrinsic biological and toxicological effects but little is known of their int...

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Bibliographic Details
Main Authors: Saghir Akhtar, Bashayer Al-Zaid, Ahmed Z El-Hashim, Bindu Chandrasekhar, Sreeja Attur, Mariam H M Yousif, Ibrahim F Benter
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4500564?pdf=render