A 6 week randomized double-blind placebo-controlled trial of ziprasidone for the acute depressive mixed state.

To examine the efficacy of ziprasidone vs. placebo for the depressive mixed state in patients with bipolar disorder type II or major depressive disorder (MDD).73 patients were randomized in a double-blinded, placebo-controlled study to ziprasidone (40-160 mg/d) or placebo for 6 weeks. They met DSM-I...

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Main Authors: Ashwin Patkar, William Gilmer, Chi-un Pae, Paul A Vöhringer, Michael Ziffra, Edward Pirok, Molly Mulligan, Megan M Filkowski, Elizabeth A Whitham, Niki S Holtzman, Sairah B Thommi, Tanya Logvinenko, Antony Loebel, Prakash Masand, S Nassir Ghaemi
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3335844?pdf=render