Molecular docking studies of salubrinal and its analogs as inhibitors of the GADD34:PP1 enzyme

Molecular docking studies of salubrinal and its analogs as inhibitors of the GADD34:PP1 enzyme

The phenomenon of the endoplasmic reticulum (ER) stress as a molecular pathophysiological process underlies diseases as cancer, diabetes mellitus, myocardial infarction, neurodegenerative disorders, diseases of the urinary system, disorders associated with bone integrity, etc. To prevent ER stress,...

Full description

Bibliographic Details
Main Authors: Pavlo V. Zadorozhnii, Ihor O. Pokotylo, Vadym V. Kiselev, Oxana V. Okhtina, Aleksandr V. Kharchenko
Format: Article
Language:English
Published: International Association of Physical Chemists (IAPC) 2019-04-01
Series:ADMET and DMPK
Subjects:
Salubrinal
molecular docking
GADD34:PP1
RMSD
endoplasmic reticulum stress
Online Access:http://pub.iapchem.org/ojs/index.php/admet/article/view/632

Similar Items

Similar Items