The Prevention of Brain Metastases in Non-Small Cell Lung Cancer by Prophylactic Cranial Irradiation

The Prevention of Brain Metastases in Non-Small Cell Lung Cancer by Prophylactic Cranial Irradiation

BackgroundNon-small cell lung cancer (NSCLC) patients frequently develop brain metastases (BM), even though the initial imaging with brain CT or MRI was negative. Stage III patients have the highest risk to develop BM, with an incidence of approximately 30%. BM can lead to neurocognitive disorders,...

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Bibliographic Details
Main Authors: Willem J. A. Witlox, Bram L. T. Ramaekers, Jaap D. Zindler, Daniëlle B. P. Eekers, Judith G. M. van Loon, Lizza E. L. Hendriks, Anne-Marie C. Dingemans, Dirk K. M. De Ruysscher
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-07-01
Series:Frontiers in Oncology
Subjects:
non-small cell lung cancer
prophylactic cranial irradiation
brain metastases
toxicity
survival
quality of life
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2018.00241/full

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https://www.frontiersin.org/article/10.3389/fonc.2018.00241/full

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