Lymphatic Endothelial Cell Activation and Dendritic Cell Transmigration Is Modified by Genetic Deletion of Clever-1

Lymphatic Endothelial Cell Activation and Dendritic Cell Transmigration Is Modified by Genetic Deletion of Clever-1

Clever-1 also known as Stabilin-1 and FEEL-1 is a scavenger molecule expressed on a subpopulation of anti-inflammatory macrophages and lymphatic endothelial cells (LECs). However, its role in regulating dendritic cell (DC) trafficking and subsequent effects on immunity have remained unexplored. In t...

Full description

Bibliographic Details
Main Authors: Sina Tadayon, Johannes Dunkel, Akira Takeda, Dominik Eichin, Reetta Virtakoivu, Kati Elima, Sirpa Jalkanen, Maija Hollmén
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-03-01
Series:Frontiers in Immunology
Subjects:
dendritic cells
lymphatics
lymphatic vessels
traffic
migration
immunosuppression
Online Access:https://www.frontiersin.org/articles/10.3389/fimmu.2021.602122/full

Internet

https://www.frontiersin.org/articles/10.3389/fimmu.2021.602122/full

Similar Items