Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway

Siglec-15 Promotes Tumor Progression in Osteosarcoma via DUSP1/MAPK Pathway

Recurrence and metastasis are important features of osteosarcoma (OS) that cause its poor prognosis. Aberrant expression of Sialic acid-binding immunoglobulin-like lectin 15 (Siglec-15) has been reported in various kinds of cancers. However, the expression and function of Siglec-15 in OS remain uncl...

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Bibliographic Details
Main Authors: Meng-ke Fan, Guo-chuan Zhang, Wei Chen, Li-li Qi, Ming-fang Xie, Yue-yao Zhang, Ling Wang, Qi Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-07-01
Series:Frontiers in Oncology
Subjects:
osteosarcoma
Siglec-15
immune response
DUSP1
MAPK
Online Access:https://www.frontiersin.org/articles/10.3389/fonc.2021.710689/full

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https://www.frontiersin.org/articles/10.3389/fonc.2021.710689/full

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