RNA-Protein Interaction Analysis of SARS-CoV-2 5′ and 3′ Untranslated Regions Reveals a Role of Lysosome-Associated Membrane Protein-2a during Viral Infection

ABSTRACT Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is a positive-strand RNA virus. The viral genome is capped at the 5′ end, followed by an untranslated region (UTR). There is a poly(A) tail at the 3′ end, preceded by a UTR. The self-interaction between the RNA regulatory elements...

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Bibliographic Details
Main Authors: Rohit Verma, Sandhini Saha, Shiv Kumar, Shailendra Mani, Tushar Kanti Maiti, Milan Surjit
Format: Article
Language:English
Published: American Society for Microbiology 2021-08-01
Series:mSystems
Subjects:
Online Access:https://journals.asm.org/doi/10.1128/mSystems.00643-21