Role of 11β-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure

Role of 11β-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure

Aldosterone concentrations vary in advanced chronic renal failure (CRF). The isozyme 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2), which confers aldosterone specificity for mineralocorticoid receptors in distal tubules and collecting ducts, has been reported to be decreased or nor...

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Bibliographic Details
Main Authors:	N.L. Yeyati, M.E. Altuna, M.C. Damasco, M.A. Mac Laughlin
Format:	Article
Language:	English
Published:	Associação Brasileira de Divulgação Científica 2010-01-01
Series:	Brazilian Journal of Medical and Biological Research
Subjects:	Aldosterone 5/6 Nephrectomy 11β-HSD2 Potassium excretion
Online Access:	http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000100008

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