Role of 11β-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure

Role of 11β-hydroxysteroid dehydrogenase 2 renal activity in potassium homeostasis in rats with chronic renal failure

Aldosterone concentrations vary in advanced chronic renal failure (CRF). The isozyme 11β-hydroxysteroid dehydrogenase 2 (11β-HSD2), which confers aldosterone specificity for mineralocorticoid receptors in distal tubules and collecting ducts, has been reported to be decreased or nor...

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Bibliographic Details
Main Authors: N.L. Yeyati, M.E. Altuna, M.C. Damasco, M.A. Mac Laughlin
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2010-01-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
Aldosterone
5/6 Nephrectomy
11β-HSD2
Potassium excretion
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000100008

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http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2010000100008

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