In silico design and optimization of selective membranolytic anticancer peptides
Abstract Membranolytic anticancer peptides represent a potential strategy in the fight against cancer. However, our understanding of the underlying structure-activity relationships and the mechanisms driving their cell selectivity is still limited. We developed a computational approach as a step tow...
| Main Authors: | , , , , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Nature Publishing Group
2019-08-01
|
| Series: | Scientific Reports |
| Online Access: | https://doi.org/10.1038/s41598-019-47568-9 |