Biochemical effects of combined action of γ-irradiation and paclitaxel on anaplastic thyroid cancer cells

The aim of the paper was to describe the biochemical effects of Paclitaxel (Ptx), γ-irradiation (IR) and their combination in undifferentiated thyroid cancer cells (ATC). IR activated common DNA damage-induced signaling and manifested certain mitogenic effect by inactivation of retinoblastoma protei...

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Bibliographic Details
Main Authors: V. M. Pushkarev, O. I. Kovzun, V. V. Pushkarev, M. D. Tronko
Format: Article
Language:English
Published: National Academy of Sciences of Ukraine and Palladin Institute of Biochemistry of the National Academy of Sciences of Ukraine. 2013-02-01
Series:Ukrainian Biochemical Journal
Subjects:
Online Access:http://ukrbiochemjournal.org/wp-content/uploads/2015/07/Pushkarev_1_13.pdf