Whole blood transfusion improves vascular integrity and increases survival in artemether-treated experimental cerebral malaria

Abstract Pathological features observed in both human and experimental cerebral malaria (ECM) are endothelial dysfunction and changes in blood components. Blood transfusion has been routinely used in patients with severe malarial anemia and can also benefit comatose and acidotic malaria patients. In...

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Bibliographic Details
Main Authors: Saba Gul, Flavia L. Ribeiro-Gomes, Aline S. Moreira, Guilherme S. Sanches, Fabiana G. Conceição, Cláudio Tadeu Daniel-Ribeiro, Hans C. Ackerman, Leonardo J. M. Carvalho
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-91499-3