Sonic hedgehog regulates osteoblast function by focal adhesion kinase signaling in the process of fracture healing.

Several biological studies have indicated that hedgehog signaling plays an important role in osteoblast proliferation and differentiation, and sonic hedgehog (SHH) expression is positively correlated with phosphorylated focal adhesion kinase (FAK) Tyr(397). However, the relationship between them and...

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Bibliographic Details
Main Authors: Yuu Horikiri, Tsuyoshi Shimo, Naito Kurio, Tatsuo Okui, Kenichi Matsumoto, Masahiro Iwamoto, Akira Sasaki
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3790742?pdf=render