Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

Efficacy and Blood Plasmalogen Changes by Oral Administration of Plasmalogen in Patients with Mild Alzheimer's Disease and Mild Cognitive Impairment: A Multicenter, Randomized, Double-blind, Placebo-controlled Trial

Background: Plasmalogens (Pls) reportedly decreased in postmortem brain and in the blood of patients with Alzheimer's disease (AD). Recently we showed that intraperitoneal administration of Pls improved cognitive function in experimental animals. In the present trial, we tested the efficacy of...

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Bibliographic Details
Main Authors: Takehiko Fujino, Tatsuo Yamada, Takashi Asada, Yoshio Tsuboi, Chikako Wakana, Shiro Mawatari, Suminori Kono
Format: Article
Language:English
Published: Elsevier 2017-03-01
Series:EBioMedicine
Subjects:
Plasmalogen
Scallop
Alzheimer's disease
Mild cognitive impairment
Cognitive function
Online Access:http://www.sciencedirect.com/science/article/pii/S2352396417300713

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http://www.sciencedirect.com/science/article/pii/S2352396417300713

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