Regulation of TB vaccine-induced airway luminal T cells by respiratory exposure to endotoxin.

Tuberculosis (TB) vaccine-induced airway luminal T cells (ALT) have recently been shown to be critical to host defense against pulmonary TB. However, the mechanisms that maintain memory ALT remain poorly understood. In particular, whether respiratory mucosal exposure to environmental agents such as...

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Bibliographic Details
Main Authors: Xuerong Chen, Fangming Xiu, Carly N Horvath, Daniela Damjanovic, Niroshan Thanthrige-Don, Mangalakumari Jeyanathan, Zhou Xing
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3402539?pdf=render