The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history

The rights and wrongs of blood-brain barrier permeability studies: a walk through 100 years of history

Careful examination of relevant literature shows that many of the most cherished concepts of the blood-brain barrier are incorrect. These include an almost mythological belief in its immaturity that is unfortunately often equated with absence or at least leakiness in the embryo and fetus. The origin...

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Bibliographic Details
Main Authors: Norman Ruthven Saunders, Jean Jacques eDreifuss, Katarzyna eDziegielewska, Pia eJohansson, Mark eHabgood, Kjeld eMøllgård, Hans-Christian eBauer
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-12-01
Series:Frontiers in Neuroscience
Subjects:
Blood-Brain Barrier
Fetus
Permeability
Tight Junctions
transporters
embryo
Online Access:http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00404/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fnins.2014.00404/full

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