Iron-enriched diet contributes to early onset of osteoporotic phenotype in a mouse model of hereditary hemochromatosis.

Osteoporosis is associated with chronic iron overload secondary to hereditary hemochromatosis (HH), but the causative mechanisms are incompletely understood. The main objective of this study was to investigate the role of dietary iron on osteoporosis, using as biological model the Hfe-KO mice, which...

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Bibliographic Details
Main Authors: Márcio Simão, António Camacho, Agnès Ostertag, Martine Cohen-Solal, I Jorge Pinto, Graça Porto, Ea Hang Korng, M Leonor Cancela
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6241130?pdf=render