Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain

Detection of the LINE-1 retrotransposon RNA-binding protein ORF1p in different anatomical regions of the human brain

Abstract Background Recent reports indicate that retrotransposons – a type of mobile DNA – can contribute to neuronal genetic diversity in mammals. Retrotransposons are genetic elements that mobilize via an RNA intermediate by a “copy-and-paste” mechanism termed retrotransposition. Long Interspersed...

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Bibliographic Details
Main Authors: Debpali Sur, Raj Kishor Kustwar, Savita Budania, Anita Mahadevan, Dustin C. Hancks, Vijay Yadav, S. K. Shankar, Prabhat K. Mandal
Format: Article
Language:English
Published: BMC 2017-11-01
Series:Mobile DNA
Subjects:
Retrotransposon
LINE-1
ORF1p antibody
Active retrotransposition in human brain
Somatic mosaicism
Online Access:http://link.springer.com/article/10.1186/s13100-017-0101-4

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http://link.springer.com/article/10.1186/s13100-017-0101-4

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