Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria

Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria

Abstract Phosphatidic acid phosphatase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis. PAP activity has a key role in the regulation of PA flux towards TAG or glycerophospholipid synthesis. In...

Full description

Bibliographic Details
Main Authors:	Agostina Crotta Asis, Franco Savoretti, Matías Cabruja, Hugo Gramajo, Gabriela Gago
Format:	Article
Language:	English
Published:	Nature Publishing Group 2021-06-01
Series:	Scientific Reports
Online Access:	https://doi.org/10.1038/s41598-021-92721-y

Similar Items

Role of long-chain acyl-CoAs in the regulation of mycolic acid biosynthesis in mycobacteria
by: Yi Ting Tsai, et al.
Published: (2017-01-01)

Pleiotropic effect of AccD5 and AccE5 depletion in acyl-coenzyme A carboxylase activity and in lipid biosynthesis in mycobacteria.
by: Bernardo Bazet Lyonnet, et al.
Published: (2014-01-01)

Correction: Pleiotropic Effect of AccD5 and AccE5 Depletion in Acyl-Coenzyme A Carboxylase Activity and in Lipid Biosynthesis in Mycobacteria.
by: Bernardo Bazet Lyonnet, et al.
Published: (2020-01-01)

Thematic Review Series: Glycerolipids. DGAT enzymes and triacylglycerol biosynthesis
by: Chi-Liang Eric Yen, et al.
Published: (2008-11-01)

Identification of Key Genes Associated with Triacylglycerol Biosynthesis in Avocado Fruit
by: Sung, Ha-Jung, et al.
Published: (2013)

Simulation of triacylglycerol ion profiles: bioinformatics for interpretation of triacylglycerol biosynthesis[S]
by: Rowland H. Han, et al.
Published: (2013-04-01)

Redundancy in the biosynthesis of triacylglycerol by Rhodococcus
by: Diaz Salazar Albelda, Carlos
Published: (2016)

Nitrogen deprivation induces triacylglycerol accumulation, drug tolerance and hypervirulence in mycobacteria
by: Pierre Santucci, et al.
Published: (2019-06-01)

Biosynthesis of Triacylglycerols (TAGs) in plants and algae
by: Alexandro Cagliari, et al.
Published: (2011-12-01)

Triacylglycerol biosynthesis in the rabbit mammary gland
by: Breach, R. A.
Published: (1973)

Studies on the enzyme activity and gene expression of lipid and triacylglycerol biosynthesis of cobia (Rachycentron canadum).
by: Lin-han Lee, et al.
Published: (2009)

Transcriptional Regulators of Triacylglycerol Biosynthesis in Nonseed Tissues
by: Dabbs, Parker, et al.
Published: (2014)

Identification of Acyltransferases Associated with Triacylglycerol Biosynthesis in Avocado
by: Sung, Ha-Jung
Published: (2013)

Aspects of triacylglycerol biosynthesis in developing oil-seeds
by: Griffiths, G.
Published: (1986)

A conditional mutant of the fatty acid synthase unveils unexpected cross talks in mycobacterial lipid metabolism
by: Matías Cabruja, et al.
Published: (2017-01-01)

Analysis of the transcriptome of Isodon rubescens and key enzymes involved in terpenoid biosynthesis
by: Xiuhong Su, et al.
Published: (2016-05-01)

Key enzymes of sphingolipid biosynthesis
by: Yard, Beverley A.
Published: (2008)

Identification of Acyltransferases Associated with Triacylglycerol Biosynthesis in Avocado Fruit
by: Sung, Ha-Jung, et al.
Published: (2012)

FasR Regulates Fatty Acid Biosynthesis and Is Essential for Virulence of Mycobacterium tuberculosis
by: Sonia Mondino, et al.
Published: (2020-10-01)

Identification of FadAB Complexes Involved in Fatty Acid β-Oxidation in Streptomyces coelicolor and Construction of a Triacylglycerol Overproducing strain
by: Simón Menendez-Bravo, et al.
Published: (2017-08-01)

Initiation of methylglucose lipopolysaccharide biosynthesis in mycobacteria.
by: Devinder Kaur, et al.
Published: (2009-01-01)

Phosphatidylcholine deficiency upregulates enzymes of triacylglycerol metabolism in CHO cells
by: J. Matías Caviglia, et al.
Published: (2004-08-01)

Identification, regulation and physiological role of enzymes involved in triacylglycerol and phosphatidylcholine synthesis on lipid droplets
by: Mössinger, Christine
Published: (2010)

Implications of Soluble Diacylglycerol Acyltransferases in Triacylglycerol Biosynthesis in Yeast and Plants
by: Sapa, Hima Rani
Published: (2018)

Studies of Key Enzymes Involved in the Biosynthesis of the Enediyne Antitumor Antibiotics Neocarzinostatin and C-1027
by: Cooke, Heather A.
Published: (2009)

Identification of Plant Transcription Factors that Play a Role in Triacylglycerol Biosynthesis
by: Dabbs, Parker
Published: (2015)

Progress on the Studies of the Key Enzymes of Ginsenoside Biosynthesis
by: Jin-Ling Yang, et al.
Published: (2018-03-01)

Isoprenoid biosynthesis in dandelion latex is enhanced by the overexpression of three key enzymes involved in the mevalonate pathway
by: Katharina M. Pütter, et al.
Published: (2017-05-01)

Molecular and biochemical characterisation of key enzymes involved in mycolic acid biosynthesis from Mycobacterium tuberculosis
by: Brown, Alistair Karl
Published: (2004)

Structural characterization of post-PKS enzymes involved in spinosyn biosynthesis
by: Isiorho, Eta Amauche
Published: (2015)

Biochemical Characterization of Arabidopsis Enzymes Involved in Inositol Pyrophosphate Biosynthesis
by: Adepoju, Olusegun Adeboye
Published: (2019)

Studies on enzymes involved in the biosynthesis of pterin cofactors
by: Baker, Stephen John
Published: (1997)

Purification of an enzyme involved in abscisic acid biosynthesis
by: Bass, Peter R.
Published: (1993)

Genetic and biochemical analysis of essential enzymes in triacylglycerol synthesis in arabidopsis
by: Cotton, Kimberly Lynn
Published: (2016)

DGAT enzymes are required for triacylglycerol synthesis and lipid droplets in adipocytes[S]
by: Charles A. Harris, et al.
Published: (2011-04-01)

Characterization of type-2 diacylglycerol acyltransferases in Haematococcus lacustris reveals their functions and engineering potential in triacylglycerol biosynthesis
by: Hongli Cui, et al.
Published: (2021-01-01)

Regulation of Polar Peptidoglycan Biosynthesis by Wag31 Phosphorylation in Mycobacteria
by: Lee Sang, et al.
Published: (2010-12-01)

Structural and Functional Characterization of the Enzymes Involved in the Menaquinone Biosynthesis and Benzoate Degradation
by: Mishra, Shambhavi
Published: (2013)

Molecular Cloning and Characterization of the Enzymes Involved in Flavonol Biosynthesis in Acacia confusa
by: Hwei-Choong Toh, et al.
Published: (2011)

Identification and Characterization of the Enzymes Involved in Biosynthesis of FAD and Tetrahydromethanopterin in Methanocaldococcus jannaschii
by: Mashhadi, Zahra
Published: (2014)