Characterization of key enzymes involved in triacylglycerol biosynthesis in mycobacteria

Abstract Phosphatidic acid phosphatase (PAP) catalyzes the dephosphorylation of phosphatidic acid (PA) yielding diacylglycerol (DAG), the lipid precursor for triacylglycerol (TAG) biosynthesis. PAP activity has a key role in the regulation of PA flux towards TAG or glycerophospholipid synthesis. In...

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Bibliographic Details
Main Authors: Agostina Crotta Asis, Franco Savoretti, Matías Cabruja, Hugo Gramajo, Gabriela Gago
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-021-92721-y