Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele

Mice doubly deficient in Six4 and Six5 show ventral body wall defects reproducing human omphalocele

Omphalocele is a human congenital anomaly in ventral body wall closure and may be caused by impaired formation of the primary abdominal wall (PAW) and/or defects in abdominal muscle development. Here, we report that mice doubly deficient in homeobox genes Six4 and Six5 showed the same ventral body w...

Full description

Bibliographic Details
Main Authors: Masanori Takahashi, Masaru Tamura, Shigeru Sato, Kiyoshi Kawakami
Format: Article
Language:English
Published: The Company of Biologists 2018-10-01
Series:Disease Models & Mechanisms
Subjects:
Six4/Six5
Omphalocele
Primary body wall
Coelomic epithelial cells
Mesothelium
Mouse
Online Access:http://dmm.biologists.org/content/11/10/dmm034611

Internet

http://dmm.biologists.org/content/11/10/dmm034611

Similar Items