NAD-linked mechanisms of gene de-repression and a novel role for CtBP in persistent adenovirus infection of lymphocytes

Abstract Background Adenovirus (AdV) infection is ubiquitous in the human population and causes acute infection in the respiratory and gastrointestinal tracts. In addition to lytic infections in epithelial cells, AdV can persist in a latent form in mucosal lymphocytes, and nearly 80% of children con...

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Bibliographic Details
Main Authors: Megan L. Dickherber, Charlie Garnett-Benson
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Virology Journal
Subjects:
Online Access:https://doi.org/10.1186/s12985-019-1265-y