Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes

Inconsistent Intersample ALK FISH Results in Patients with Lung Cancer: Analysis of Potential Causes

ALK FISH analyses of multiple specimens occasionally yield inconsistent intersample results in lung cancer patients, posing clinical challenges requiring intensive analysis of all potential causative pre- and post- analytic factors. In this study, 19 patients (8M/11F) with inconsistent intersample A...

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Bibliographic Details
Main Authors: Zhenya Tang, Hui Chen, Lingzhi Hong, Guilin Tang, Gokce A. Toruner, Wei Wang, Sinchita Roy Chowdhuri, Wei Yin, Hai Suk Jung, Jun Gu, Mark J. Routbort, Jianjun Zhang, Joseph D. Khoury, L. Jeffrey Medeiros
Format: Article
Language:English
Published: MDPI AG 2020-07-01
Series:Cancers
Subjects:
lung cancer
ALK
fluorescence in situ hybridization (FISH)
next-generation sequencing (NGS)
RNA sequencing (RNA-seq)
tyrosine kinase inhibitor (TKI)
Online Access:https://www.mdpi.com/2072-6694/12/7/1903

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https://www.mdpi.com/2072-6694/12/7/1903

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