Inter-Fork Strand Annealing causes genomic deletions during the termination of DNA replication
Problems that arise during DNA replication can drive genomic alterations that are instrumental in the development of cancers and many human genetic disorders. Replication fork barriers are a commonly encountered problem, which can cause fork collapse and act as hotspots for replication termination....
Main Authors: | , , , , , , |
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Format: | Article |
Language: | English |
Published: |
eLife Sciences Publications Ltd
2017-06-01
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Series: | eLife |
Subjects: | |
Online Access: | https://elifesciences.org/articles/25490 |