Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ?

Do Molecular Profiles of Primary Versus Metastatic Radioiodine Refractory Differentiated Thyroid Cancer Differ?

Management of metastatic radioiodine refractory differentiated thyroid cancer (DTC) can be a therapeutic challenge. Generally, little is known about the paired molecular profile of the primary tumor and the metastases and whether they harbor the same genetic abnormalities. The present study compared...

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Bibliographic Details
Main Authors: Cristiane J. Gomes-Lima, Leila Shobab, Di Wu, Dorina Ylli, Athanasios Bikas, Matthew McCoy, Rebecca Feldman, Wen Lee, Sarika N. Rao, Kirk Jensen, Vasily Vasko, Luiz Claudio Castro, Jacqueline Jonklaas, Leonard Wartofsky, Kenneth D. Burman
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-02-01
Series:Frontiers in Endocrinology
Subjects:
differentiated thyroid cancer
metastases
radioiodine refractory
molecular profile
next generation sequencing
Online Access:https://www.frontiersin.org/articles/10.3389/fendo.2021.623182/full

Internet

https://www.frontiersin.org/articles/10.3389/fendo.2021.623182/full

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