Poor maternal nutrition and accelerated postnatal growth induces an accelerated aging phenotype and oxidative stress in skeletal muscle of male rats

‘Developmental programming’, which occurs as a consequence of suboptimal in utero and early environments, can be associated with metabolic dysfunction in later life, including an increased incidence of cardiovascular disease and type 2 diabetes, and predisposition of older men to sarcopenia. However...

Full description

Bibliographic Details
Main Authors: Jane L. Tarry-Adkins, Denise S. Fernandez-Twinn, Jian Hua Chen, Iain P. Hargreaves, Viruna Neergheen, Catherine E. Aiken, Susan E. Ozanne
Format: Article
Language:English
Published: The Company of Biologists 2016-10-01
Series:Disease Models & Mechanisms
Subjects:
Online Access:http://dmm.biologists.org/content/9/10/1221