A pharmacokinetic model including arrival time for two inputs and compensating for varying applied flip-angle in dynamic gadoxetic acid-enhanced MR imaging.
<h4>Purpose</h4>Pharmacokinetic models facilitate assessment of properties of the micro-vascularization based on DCE-MRI data. However, accurate pharmacokinetic modeling in the liver is challenging since it has two vascular inputs and it is subject to large deformation and displacement d...
Main Authors: | Tian Zhang, Jurgen H Runge, Cristina Lavini, Jaap Stoker, Thomas van Gulik, Kasia P Cieslak, Lucas J van Vliet, Frans M Vos |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2019-01-01
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Series: | PLoS ONE |
Online Access: | https://doi.org/10.1371/journal.pone.0220835 |
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