A pharmacokinetic model including arrival time for two inputs and compensating for varying applied flip-angle in dynamic gadoxetic acid-enhanced MR imaging.

<h4>Purpose</h4>Pharmacokinetic models facilitate assessment of properties of the micro-vascularization based on DCE-MRI data. However, accurate pharmacokinetic modeling in the liver is challenging since it has two vascular inputs and it is subject to large deformation and displacement d...

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Bibliographic Details
Main Authors: Tian Zhang, Jurgen H Runge, Cristina Lavini, Jaap Stoker, Thomas van Gulik, Kasia P Cieslak, Lucas J van Vliet, Frans M Vos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0220835