Somatic substitution signature as an innovative tool in lung cancer diagnosis

Abstract Diagnosis of lung cancer can sometimes be challenging and is of major interest since effective molecular-guided therapies are available. Compounds of tobacco smoke may generate a specific substitutional signature in lung, which is the most exposed organ. To predict whether a tumor is of lun...

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Bibliographic Details
Main Authors: Stéphane Busca, Julia Salleron, Romain Boidot, Jean-Louis Merlin, Alexandre Harlé
Format: Article
Language:English
Published: Nature Publishing Group 2019-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-019-51155-3