Opposing Effects of Zac1 and Curcumin on AP-1-Regulated Expressions of S100A7.

ZAC, an encoding gene mapped at chromosome 6q24-q25 within PSORS1, was previously found over-expressed in the lower compartment of the hyperplastic epidermis in psoriatic lesions. Cytokines produced in the inflammatory dermatoses may drive AP-1 transcription factor to induce responsive gene expressi...

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Bibliographic Details
Main Authors: Yu-Wen Chu, Shu-Ting Liu, Hsiao-Chun Cheng, Shih-Ming Huang, Yung-Lung Chang, Chien-Ping Chiang, Ying-Chun Liu, Wei-Ming Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4669192?pdf=render