Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice

Transient Receptor Potential Canonical Channels 4 and 5 Mediate Escherichia coli-Derived Thioredoxin Effects in Lipopolysaccharide-Injected Mice

Thioredoxin plays an essential role in bacterial antioxidant machinery and virulence; however, its regulatory actions in the host are less well understood. Reduced human Trx activates transient receptor potential canonical 5 (TRPC5) in inflammation, but there is no evidence of whether these receptor...

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Bibliographic Details
Main Authors: Domingos M. S. Pereira, Saulo J. F. Mendes, Khadija Alawi, Pratish Thakore, Aisah Aubdool, Nágila C. F. Sousa, João F. R. da Silva, José A. Castro, Ione C. P. Pereira, Luís C. N. Silva, Marcos A. G. Grisotto, Valério Monteiro-Neto, Soraia K. P. Costa, Robson da Costa, João B. Calixto, Susan D. Brain, Elizabeth S. Fernandes
Format: Article
Language:English
Published: Hindawi Limited 2018-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2018/4904696

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http://dx.doi.org/10.1155/2018/4904696

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