Role of Mitochondria in the Mechanism(s) of Action of Metformin

Metformin is a drug from the biguanide family that is used for decades as the first-line therapeutic choice for the treatment of type 2 diabetes. Despite its worldwide democratization, owing to its clinical efficacy, high safety profile and cheap cost, the exact mechanism(s) of action of this anti-h...

Full description

Bibliographic Details
Main Authors: Guillaume Vial, Dominique Detaille, Bruno Guigas
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-05-01
Series:Frontiers in Endocrinology
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fendo.2019.00294/full