Hypothermia Modulates Cytokine Responses After Neonatal Rat Hypoxic-Ischemic Injury and Reduces Brain Damage

While hypothermia (HT) is the standard-of-care for neonates with hypoxic ischemic injury (HII), the mechanisms underlying its neuroprotective effect are poorly understood. We examined ischemic core/penumbra and cytokine/chemokine evolution in a 10-day-old rat pup model of HII. Pups were treated for...

Full description

Bibliographic Details
Main Authors: Xiangpeng Yuan, Nirmalya Ghosh, Brian McFadden, Beatriz Tone, Denise L. Bellinger, Andre Obenaus, Stephen Ashwal
Format: Article
Language:English
Published: SAGE Publishing 2014-11-01
Series:ASN Neuro
Online Access:https://doi.org/10.1177/1759091414558418