Trisulfate Disaccharide Decreases Calcium Overload and Protects Liver Injury Secondary to Liver Ischemia/Reperfusion.

Trisulfate Disaccharide Decreases Calcium Overload and Protects Liver Injury Secondary to Liver Ischemia/Reperfusion.

BACKGROUND:Ischemia and reperfusion (I/R) causes tissue damage and intracellular calcium levels are a factor of cell death. Sodium calcium exchanger (NCX) regulates calcium extrusion and Trisulfated Disaccharide (TD) acts on NCX decreasing intracellular calcium through the inhibition of the exchange...

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Bibliographic Details
Main Authors: Enio Rodrigues Vasques, Jose Eduardo Monteiro Cunha, Ana Maria Mendonca Coelho, Sandra N Sampietre, Rosely Antunes Patzina, Emilio Elias Abdo, Helena B Nader, Ivarne L S Tersariol, Marcelo Andrade Lima, Carlos M G Godoy, Tiago Rodrigues, Eleazar Chaib, Luiz A C D'Albuquerque
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4763191?pdf=render

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http://europepmc.org/articles/PMC4763191?pdf=render

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