Automated Solid-Phase Radiofluorination Using Polymer-Supported Phosphazenes

The polymer supported phosphazene bases PS-P2tBu and the novel PS-P2PEG allowed for efficient extraction of [18F]F− from proton irradiated [18O]H2O and subsequent radiofluorination of a broad range of substrates directly on the resin. The highest radiochemical yields were obtained with aliphatic sul...

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Bibliographic Details
Main Authors: Bente Mathiessen, Fedor Zhuravlev
Format: Article
Language:English
Published: MDPI AG 2013-08-01
Series:Molecules
Subjects:
Online Access:http://www.mdpi.com/1420-3049/18/9/10531