Finding of the low molecular weight inhibitors of resuscitation promoting factor enzymatic and resuscitation activity.

BACKGROUND: Resuscitation promoting factors (RPF) are secreted proteins involved in reactivation of dormant actinobacteria, including Mycobacterium tuberculosis. They have been considered as prospective targets for the development of new anti-tuberculosis drugs preventing reactivation of dormant tub...

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Main Authors: Galina R Demina, Vadim A Makarov, Vadim D Nikitushkin, Olga B Ryabova, Galina N Vostroknutova, Elena G Salina, Margarita O Shleeva, Anna V Goncharenko, Arseny S Kaprelyants
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2790607?pdf=render