Embryonic stem cell-derived L1 overexpressing neural aggregates enhance recovery after spinal cord injury in mice.

An obstacle to early stem cell transplantation into the acutely injured spinal cord is poor survival of transplanted cells. Transplantation of embryonic stem cells as substrate adherent embryonic stem cell-derived neural aggregates (SENAs) consisting mainly of neurons and radial glial cells has been...

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Bibliographic Details
Main Authors: Yi-Fang Cui, Jin-Chong Xu, Gunnar Hargus, Igor Jakovcevski, Melitta Schachner, Christian Bernreuther
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3060805?pdf=render