Growth of Murine Splenic Tissue Is Suppressed by Lymphotoxin β-Receptor Signaling (LTβR) Originating from Splenic and Non-Splenic Tissues.

Development and maintenance of secondary lymphoid organs such as lymph nodes and spleen essentially depend on lymphotoxin β-receptor (LTβR) signaling. It is unclear, however, by which molecular mechanism their size is limited. Here, we investigate whether the LTβR pathway is also growth suppressing....

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Bibliographic Details
Main Authors: Novica M Milićević, Klaus Nohroudi, Friederike Schmidt, Hendrik Schmidt, Cornelia Ringer, Grith Lykke Sorensen, Živana Milićević, Jürgen Westermann
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5147843?pdf=render