Differential contributory roles of nucleotide excision and homologous recombination repair for enhancing cisplatin sensitivity in human ovarian cancer cells

<p>Abstract</p> <p>Background</p> <p>While platinum-based chemotherapeutic agents are widely used to treat various solid tumors, the acquired platinum resistance is a major impediment in their successful treatment. Since enhanced DNA repair capacity is a major factor in...

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Bibliographic Details
Main Authors: Wani Gulzar, Huang Yi-Wen, Han Chunhua, Milum Keisha, Wang Qi-En, Thomale Jürgen, Wani Altaf A
Format: Article
Language:English
Published: BMC 2011-03-01
Series:Molecular Cancer
Online Access:http://www.molecular-cancer.com/content/10/1/24