Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice

Mtrr hypomorphic mutation alters liver morphology, metabolism and fuel storage in mice

Nonalcoholic fatty liver disease (NAFLD) is associated with dietary folate deficiency and mutations in genes required for one‑carbon metabolism. However, the mechanism through which this occurs is unclear. To improve our understanding of this link, we investigated liver morphology, metabolism and fu...

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Bibliographic Details
Main Authors: Alice P. Sowton, Nisha Padmanabhan, Simon J. Tunster, Ben D. McNally, Antonio Murgia, Aisha Yusuf, Julian L. Griffin, Andrew J. Murray, Erica D. Watson
Format: Article
Language:English
Published: Elsevier 2020-06-01
Series:Molecular Genetics and Metabolism Reports
Subjects:
One‑carbon metabolism
Liver metabolism
Hepatic fuel storage
Glycogen
Lipidomics
Mitochondrial function
Online Access:http://www.sciencedirect.com/science/article/pii/S2214426920300264

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http://www.sciencedirect.com/science/article/pii/S2214426920300264

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