Modulation of mitochondrial activity in HaCaT keratinocytes by the cell penetrating peptide Z-Gly-RGD(DPhe)-mitoparan

Modulation of mitochondrial activity in HaCaT keratinocytes by the cell penetrating peptide Z-Gly-RGD(DPhe)-mitoparan

Abstract Objective Biologically active cell penetrating peptides (CPPs) are an emerging class of therapeutic agent. The wasp venom peptide mastoparan is an established CPP that modulates mitochondrial activity and triggers caspase-dependent apoptosis in cancer cells, as does the mastoparan analogue...

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Bibliographic Details
Main Authors: Adam Richardson, Lewis Muir, Sasha Mousdell, Darren Sexton, Sarah Jones, John Howl, Kehinde Ross
Format: Article
Language:English
Published: BMC 2018-01-01
Series:BMC Research Notes
Subjects:
Cell penetrating peptides
Bioportides
Keratinocytes
Mitochondria
Online Access:http://link.springer.com/article/10.1186/s13104-018-3192-1

Internet

http://link.springer.com/article/10.1186/s13104-018-3192-1

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