Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs

Comparison of total and cytoplasmic mRNA reveals global regulation by nuclear retention and miRNAs

<p>Abstract</p> <p>Background</p> <p>The majority of published gene-expression studies have used RNA isolated from whole cells, overlooking the potential impact of including nuclear transcriptome in the analyses. In this study, mRNA fractions from the cytoplasm and from...

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Bibliographic Details
Main Authors: Solnestam Beata, Stranneheim Henrik, Hällman Jimmie, Käller Max, Lundberg Emma, Lundeberg Joakim, Akan Pelin
Format: Article
Language:English
Published: BMC 2012-10-01
Series:BMC Genomics
Subjects:
Differential detection
Gene expression
Nuclear retention
miRNA regulation
RNA-Seq
Online Access:http://www.biomedcentral.com/1471-2164/13/574

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http://www.biomedcentral.com/1471-2164/13/574

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