Generating CAR T cells from tumor-infiltrating lymphocytes

Generating CAR T cells from tumor-infiltrating lymphocytes

Background: Tumor-infiltrating lymphocytes (TILs) and chimeric antigen receptor (CAR) T-cell therapies have demonstrated promising, though limited, efficacy against melanoma. Methods: We designed a model system to explore the efficacy of dual specific T cells derived from melanoma patient TILs by tr...

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Bibliographic Details
Main Authors: Jane K. Mills, Melissa A. Henderson, Lauren Giuffrida, Pasquale Petrone, Jennifer A. Westwood, Phillip K. Darcy, Paul J. Neeson, Michael H. Kershaw, David E. Gyorki
Format: Article
Language:English
Published: SAGE Publishing 2021-05-01
Series:Therapeutic Advances in Vaccines and Immunotherapy
Online Access:https://doi.org/10.1177/25151355211017119

Internet

https://doi.org/10.1177/25151355211017119

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